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Health Point Prevalence of TB Among Sars Cov-2 Positive Patients in Delta State

Tarurhor, Love Eguonor, Ehwarieme, Ayobola D., Jemikalajah, D. Johnson,

Abstract

COVID-19 and tuberculosis (TB) overlap in clinical presentation, complicating diagnosis in TB- endemic regions. Data on TB prevalence among SARS-CoV-2–seropositive patients in Delta state, Nigeria are scarce. The aim of this research is to determine TB prevalence among SARS-CoV-2 antibody–positive patients in Delta State, Nigeria. A cross-sectional study enrolled 154 patients with respiratory symptoms from three hospitals. Venous blood was collected for SARS-CoV-2 antibody testing, and sputum samples were analyzed for TB using GeneXpert MTB/RIF. Descriptive statistics summarized participant characteristics, and Chi-square tests assessed associations between TB/SARS-CoV-2 co-infection and age, gender, and study site. SARS-CoV-2 antibodies were detected in 98 participants (63.6%). Among these, 31 (31.6%) had TB co- infection. Co-infection was highest in Warri (38.7%), followed by Asaba (33.3%) and Ughelli (25.0%). Adults aged 31–45 years had the highest co-infection rate (15.3%). Females had slightly higher prevalence than males (51.6% vs. 48.4%). No statistically significant associations were observed between co-infection and site, age, or gender (p > 0.05). in conclusion, SARS-CoV-2 exposure is widespread in Delta State, with a substantial proportion of seropositive individuals co-infected with TB. Adults aged 31–45 years and females appear most affected. These findings highlight the urgent need for integrated TB and COVID-19 screening programs in high-burden settings to enable timely diagnosis and improve patient outcomes.

Keywords

Tuberculosis co-infectionSars CoV-2 AntibodiesPrevalenceSeroprevalenceEpidermiology

References

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