References
[1] Roglic, G. (2016). WHO Global report on diabetes: A summary. International Journal of Noncommunicable Diseases, 1(1), 3-8. [2] Sapra, A., & Bhandari, P. (2023). Continuing Education Activity. Diabetes. [3] Steyl, T. (2020). Satisfaction with quality of healthcare at primary healthcare settings: Perspectives of patients with type 2 diabetes mellitus. South African Journal of Physiotherapy, 76(1), 1-7. [4] Ogurtsova, K., da Rocha Fernandes, J. D., Huang, Y., Linnenkamp, U., Guariguata, L., Cho, N. H., ... & Makaroff, L. E. (2017). IDF Diabetes Atlas: Global estimates for the prevalence of diabetes for 2015 and 2040. Diabetes research and clinical practice, 128, 40-50. [5] Lin, X., Xu, Y., Pan, X., Xu, J., Ding, Y., Sun, X., ... & Shan, P. F. (2020). Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025. Scientific reports, 10(1), 1-11. [6] Standl, E., Khunti, K., Hansen, T. B., & Schnell, O. (2019). The global epidemics of diabetes in the 21st century: Current situation and perspectives. European journal of preventive cardiology, 26(2_suppl), 7-14. [7] Ong, K. L., Stafford, L. K., McLaughlin, S. A., Boyko, E. J., Vollset, S. E., Smith, A. E., ... & Brauer, M. (2023). Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study The Lancet, 402(10397), 203-234. [8] Koye, D. N., Magliano, D. J., Nelson, R. G., & Pavkov, M. E. (2018). The global epidemiology of diabetes and kidney disease. Advances in chronic kidney disease, 25(2), 121-132. [9] Xiao-Ping, Y. E., Chun-Qing, S. O. N. G., Ping, Y. U. A. N., & Ren-Gang, M. A. O. (2010). ?-Glucosidase and ?-amylase inhibitory activity of common constituents from traditional Chinese medicine used for diabetes mellitus. Chinese Journal of Natural Medicines, 8(5), 349-352. [10] Lin, X., Xu, Y., Pan, X., Xu, J., Ding, Y., Sun, X., ... & Shan, P. F. (2020). Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025. Scientific reports, 10(1), 1-11. [11] Haguet, Q., Le Joubioux, F., Chavanelle, V., Groult, H., Schoonjans, N., Langhi, C., ... & Maugard, T. (2023). Inhibitory potential of ?-amylase, ?-glucosidase, and pancreatic lipase by a formulation of five plant extracts: TOTUM-63. International Journal of Molecular Sciences, 24(4), 3652. [12] Jiang, J., Fan, H., Zhou, J., Qin, J., Qin, Z., Chen, M., ... & Liu, X. (2024). In vitro inhibitory effect of five natural sweeteners on ?-glucosidase and ?-amylase. Food & Function, 15(4), 2234- [13] Abdul Basith Khan, M., Hashim, M. J., King, J. K., Govender, R. D., Mustafa, H., & Al Kaabi, J. (2020). Epidemiology of type 2 diabetes—global burden of disease and forecasted trends. Journal of epidemiology and global health, 10(1), 107-111. [14] Arora, K., Tomar, P. C., & Mohan, V. (2021). Diabetic neuropathy: an insight on the transition from synthetic drugs to herbal therapies. Journal of Diabetes & Metabolic Disorders, 20(2), 1773- [15] Pang, G. M., Li, F. X., Yan, Y., Zhang, Y., Kong, L. L., Zhu, P., ... & Lu, C. (2019). Herbal medicine in the treatment of patients with type 2 diabetes mellitus. Chinese medical journal, 132(1), 78-85. [16] Builders, P. F., Mohammed, B. B., & Sule, Y. Z. (2020). Preparation and evaluation of the physicochemical and stability properties of three herbal tea blends derived from four native herbs. Journal of Phytomedicine and Therapeutics, 19(2), 448-465. [17] Golak-Siwulska, I., Ka?u?ewicz, A., Spi?ewski, T., Siwulski, M., & Sobieralski, K. (2018). Bioactive compounds and medicinal properties of Oyster mushrooms (sp.). Folia Horticulturae, 30(2), 191-201. [18] Rahman, N., Tangkas, I. M., Rakhman, A., Sabang, S. M., & Bohari, B. (2022). Effect of avocado (Persea americana Mill.) peel extract on the diabetic male white rats: preclinical study. Open Access Macedonian Journal of Medical Sciences, 10(A), 415-418. [19] Oboh, G., Isaac, A. T., Akinyemi, A. J., & Ajani, R. A. (2014). Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside induced lipid peroxidation in rats’ pancreas by phenolic extracts of avocado pear leaves and fruit. International Journal of Biomedical Science: IJBS, 10(3), 208. [20] Ameer, K. (2016). Avocado as a major dietary source of antioxidants and its preventive role in neurodegenerative diseases. The benefits of natural products for neurodegenerative diseases, 337-354. [21] Jimenez, P., Garcia, P., Quitral, V., Vasquez, K., Parra-Ruiz, C., Reyes-Farias, M., ... & Soto- Covasich, J. (2021). Pulp, leaf, peel and seed of avocado fruit: A review of bioactive compounds and healthy benefits. Food Reviews International, 37(6), 619-655. [22] Pagadala, N. S., Syed, K., & Tuszynski, J. (2017). Software for molecular docking: a review. Biophysical reviews, 9, 91-102. [23] Gioia, D., Bertazzo, M., Recanatini, M., Masetti, M., & Cavalli, A. (2017). Dynamic docking: a paradigm shift in computational drug discovery. Molecules, 22(11), 2029. [24] Sam Paul, D., & Gautham, N. (2018). Protein–small molecule docking with receptor flexibility in iMOLSDOCK. Journal of Computer-Aided Molecular Design, 32, 889-900. [25] I. A. Guedes, F.S. Pereira & L.E. Dardenne, "Empirical scoring functions for structure-based virtual screening: applications, critical aspects, and challenges", Frontiers in pharmacology 9 (2018): 1089. [26] Kim, S., Chen, J., Cheng, T., Gindulyte, A., He, J., He, S., ... & Bolton, E. E. (2021). PubChem in 2021: new data content and improved web interfaces. Nucleic acids research, 49(D1), D1388- D1395. [27] Lohohola, P. O., Mbala, B. M., Bambi, S. M. N., Mawete, D. T., Matondo, A., & Mvondo, J. G. M. (2021). In silico ADME/T properties of quinine derivatives using SwissADME and pkCSM webservers. International Journal of TROPICAL DISEASE & Health, 42(11), 1-12. [28] Sim, L., Quezada-Calvillo, R., Sterchi, E. E., Nichols, B. L., & Rose, D. R. (2008). Human intestinal maltase–glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity. Journal of Molecular Biology, 375(3), 782-792. [29] Krentz, A. J., & Bailey, C. J. (2005). Oral antidiabetic agents: current role in type 2 diabetes mellitus. Drugs, 65, 385-411. [30] Zhang, R., Li, C., Williams, L. K., Rempel, B. P., Brayer, G. D., & Withers, S. G. (2009). Directed “in situ” inhibitor elongation as a strategy to structurally characterize the covalent glycosyl-enzyme intermediate of human pancreatic ?-amylase. Biochemistry, 48(45), 10752- 10764.