Phytochemical And Antimicrobial Activities of Seed Ethanolic Extract of African Walnut on Selected Pathogens

Abstract

African walnuts is a member of the euphorbiaceae the genus plukentia. Phytochemical and antimicrobial activities of African walnut (Teracarpidium conophorum) ethanolic extract were investigated. The effect of this seed was examined on 3 selected groups of microorganisms. Escherichia coliwere selected among gram negative bacteria. Staphylococcus aureus among gram positive bacteria. While among group of fungi Candida albican was selected. The extraction of active substance was done by soaking the dried powered seed in ethanol for 72hours and it was evaporated using water bath at required temperature. Disc diffusion method was used for examination of antimicrobial activities of the extract. Result shows that the extract has little effect on Escherichia coli, it has no effect on Staphylococcus aureusas well as Candida albican. Phytochemical Constituents presence were alkaloids, flavonoids, terpenoids, tannis, sapannin, glycosides and anthiaquinones. The presence of these phytochemical constituents supports its uses in herbal medicine as therapeutic agent. More research has to be done on the importance of oil fraction of this seed plant

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