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Anesthetics and Analgesics: Ketamine Use and Regulation in Ghana

Prince Opuni Frimpong

Abstract

Objectives: Apply PICOT framework analyzing literature on ketamine utilization for anesthesia/analgesia in Ghanaian healthcare facilities to inform policy and practice. Methods: Structured analysis of clinical studies, Ghana Health Service guidelines and databases for trends in efficacy, safety, compliance and access from diverse regions and surgical settings from 2000-2022. Results: Evidence supports ketamine effectiveness but gaps in administration standards adherence, monitoring availability and prescribing oversight threaten patient safety while denying access for remote areas. Conclusions: Balanced regulation updates relaxing provider mandates while standardizing training, reporting requirements and infrastructure upgrades can optimize ketamine’s unique benefits and accessibility for equitable surgical capacity. Scientific Contributions: Original analysis of multi-site compliance rates to usage standards. This policy analysis used pharmacoepidemiologic methods examining impacts of essential medicine guideline adjustments. Practical Significance: Strategic roadmap tailored to resource limitations with discrete recommendations from staffing to digital access to improve judicious use. Recommendations: Target training, administration protocols, inventory tracking, monitoring availability, unified reporting and licensing enforcement.

Keywords

Ketamine; Anesthesia; Analgesia; Ghana; Regulation; Compliance

References

Aduful, H. K., Kwaw, K. A., Okyere, E., & Dako-Gyeke, P. (2007). Propofol vs ketamine for conscious sedation in endoscopic retrograde choledochopancreatography (ERCP) procedure: An open-label comparative randomized control trial. Ghana medical journal, 41(9), 34–39. Amuchia, I., Nguemegne, D., Ngamgbe, K., Azantsa, K., Tchoumbou, C., Mboua, P., Ngowe- Ngowe, M. (2021). Combining low dose morphine and ketamine intravenous infusions in the emergency analgesia of trauma patients in a hospital without a functional anesthesia machine: a prospective open-labeled study. Pan African Medical Journal, 38(184). Andoh, K. T., Andem, B., Kporvi, S., Annan, S. E., Kodom, A. S., Aziato, L., & Obeng, B. (2022). Post Caesarean Section Pain Management; Intramuscular Ketamine Versus Diclofenac. Current Therapeutic Research, 103, 100846.

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