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Progressive Supranuclear Palsy: A case report in Southern Nigeria

Ezunu Okechukwu Emmanuel , Akpekpe John , Yusuf Yakub , Osiatuma Victor Azubuike , Okojie Promise Joseph

Abstract

Progressive supranuclear palsy (PSP) is a progressive neurodegenerative clinical disorder. It is often diagnosed as Parkinson's disease due to the similar clinical presentation of these neurodegenerative disorders. Diagnosing PSP in low-medium-income countries such as Nigeria can be challenging as it is more of a diagnosis of exclusion and this relies largely on neuroimaging. The increasing availability of MRI in Nigeria in the last decade has helped to shore up the level of diagnostic certainty of this condition.

Keywords

ProgressivesupranuclearpalsyMagnetic resonance imaging (MRI)

References

1. Steele JC, Richardson JC, Olszewski J. Progressive Supranuclear Palsy: A Heterogeneous Degeneration Involving the Brain Stem, Basal Ganglia and Cerebellum With Vertical Gaze and Pseudobulbar Palsy, Nuchal Dystonia, and Dementia. Archives of Neurology. 1964;10:333-59. 2. Ali Shoeibi, Nahid Olfati, Irene Latvan: Frontrunner in Translation; Progressive Supranuclear palsy, Frontiers in Neurology, October 2019/volume10/article1125. 3. Garbor G Kovacs, Milica Jecmenica Lukic et al: Distribution patterns of tau pathology in progressive supranuclear palsy; Acta Neuropathol. 2020 Aug;140(2):99-119. doi: 10.1007/s00401-020-02158-2. Epub 2020 May 7....

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