IIARD International Institute of Academic Research and Development

INTERNATIONAL JOURNAL OF HEALTH AND PHARMACEUTICAL RESEARCH (IJHPR )

E-ISSN 2545-5737
P-ISSN 2695-2165
VOL. 8 NO. 3 2023
DOI: 10.56201/ijhpr.v8.no3.2023.pg136.147

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Antibacterial Efficacy of Adamsonia Digitata Stem Bark Crude Extracts Against Staphylococcus Aureus and Shigella Dysenteriae

Kashari, O., Abdulkadir, M, Samira, A., Farooq, U and Attah, O.A

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Abstract

This research work on the antibacterial efficacy of Adamsonia digitata crude stem bark extracts against Staphylococcus aureus and Shigella dysenteriae, was conducted using Disc diffusion method, on the ethanol and aqueous crude extracts of Adamsonia digitata stem bark against Staphylococcus aureus and Shigella dysenteriae. The crude extracts were effective at all the concentrations (10, 30, 50 and 70 mg/ml) used on the test bacteria. The ethanol crude extract indicates high antibacterial efficacy of 6.0, 12.0, 16,0, 16.0mm and 10.0, 16.0, 16.0 and 16.0mm with all the concentrations used against Staphylococcus aureus and Shigella dysenteriae respectively while the aqueous crude extract also indicates activity of 6.0, 12.0, 16,0, 20.0mm and 12.0, 16.0, 16.0 and 16.0mm all all the concentrations used against Staphylococcus aureus and Shigella dysenteriae. Ciprofloxacin impregnanted antibiotic disc was used as positive control which indicates activity of 18.0 and 20.0 against Staphylococcus aureus and Shigella dysenteriae. The minimum inhibitory concentration (MIC) and the minimum bactericidal study of ethanol and aqueous stem bark crude extracts of Adamsonia digitata against Staphylococcus aureus and Shigella dysenteriae indicates that the plant part used is potent against the test bacteria under study. The phytochhemical screening of the stem bark crude extracts of the plant showed the present of alkanoids, saponins, tannins, flavonoids, terpeniods, glycoside and Anthraquinose. This research work is pointer of the possible used of Adamsonia digitata stem bark crude extracts as remedy for the treatment of infections or disorders cause by these bacteria under study.

keywords:

Adamsonia digitata, antibacterial, efficacy, Staphylococcus aureus, Shigella dysenteriae, diffusion, determine.

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