Submit your papers Submit Now
International Peer-Reviewed Journal
For Enquiries: editor@iiardjournals.org
📄 Download Paper

Effects of Polycyclic Aromatic Hydrocarbon on Hematological Parameters of Exposed Individuals

Ekeh Stellaa Okoro and Joshua Charles Isirima b

Abstract

Serious consequences for public health result from exposure to harmful substances, particularly in the workplace. To what extent might exposure to petroleum and its byproducts impact human metabolism was the overarching issue that motivated this investigation. Using a sterile needle, 10 persons were picked from each of the following groups: the control group in Umuahia, the filling station attendants in the Choba district, and the motor mechanics and craftsmen departing from Mbodo Aluu. The hematological indices showed the following: PCV 24.50 (APH) to 44.60 (Control), HB(g/dl) 7.51 (APH) to 13.22 (Control), RBC(X1012/l) 2.45 (APH) to 6.13 (MAFL), WBC(X109/l) 5.63 (APH) to 37,000 (Control), Platelet(X109/l) 135 (MW) to 1416,000 (Control), MCV 4.01 (MW) to 6.70 (Control), MCH 2.37 (Control) to 3.72 (MW), and MCHC 0.307 (APH, MAFL, MW) to 0.308 (Control). There was little to no deviation from control values in the MCV, MCH, and MCHC results. Nevertheless, the experimental and control groups showed a significant disparity in PCV, HB, RBC, WBC, and platelet count at a confidence level of p<0.05. The results of this research suggest that polycyclic aromatic hydrocarbons may have a detrimental effect on the evaluated biochemical parameter's health.

References

Basaran, B.; Y?lmaz Civan, M. (2021). Investigating of primary components and sourceapportionment of persistent organic pollutants of indoor dust. Environ. Sci. Technol. 18, 2145–2160. [Google Scholar] [CrossRef] Bostrom CE, Gerde P, Hanberg A, Jernstrom B, Johansson C, Kyrklund T, Rannug A, Tornqvist M, Victorin K, Westerholm R (2002). Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air. Environ Health Perspect. 110(Suppl 3):451–88. Davoudi, M.; Esmaili-Sari, A.; Bahramifar, N. Moeinaddini, M. (2021). Spatio-temporal variation and risk assessment of polycyclic aromatic hydrocarbons (PAHs) in surface dust of Qom metropolis, Iran. Environ. Sci. Pollut. Res. 28, 9276–9289. [Google Scholar] [CrossRef] Ihsanullah, I.; Atieh, M.A.; Sajid, M.; Nazal, M.K. (2021). Desalination and environment: A critical analysis of impacts, mitigation strategies, and greener desalination technologies. Sci. Total Environ. 780, 146585. [Google Scholar] [CrossRef] Padmanaban, D. and Todra, G. (2011). Inkosi Albert Luthuli Central Hospital. Proceedings of South African Thalassaemia Association. Premnath, N.; Mohanrasu, K.; Rao, R.G.R.; Dinesh, G.H.; Prakash, G.S.; Pugazhendhi, A.; Jeyakanthan, J.; Govarthanan, M.; Kumar, P.; Arun, A. (2021). Effect of C/N substrates for enhanced extracellular polymeric substances (EPS) production and Poly Cyclic Aromatic Hydrocarbons (PAHs) degradation. Environ. Pollut. 275, 116035. [Google Scholar] [CrossRef] Xu X, Cook RL, Ilacqua VA, Kan H, Talbott EO, Kearney G. (2010) Studying associations between urinary metabolites of polycyclic aromatic hydrocarbons (PAHs) and cardiovascular diseases in the United States. Sci Total Environ. 408(21):4943–8. Zubieta, J., Bakea, T.G., Parapia, L.A., Khoury, S.A., Shugaidef, S.W. and Jerwood, D. , (2007). Anaemia during pregnancy as a risk factor for iron-deficiency E. anaemia in infancy: a case-control study in Jordan. International Journal E, of Epidemiology 28:461-468.