IIARD International Institute of Academic Research and Development

INTERNATIONAL JOURNAL OF HEALTH AND PHARMACEUTICAL RESEARCH (IJHPR )

E-ISSN 2545-5737
P-ISSN 2695-2165
VOL. 10 NO. 3 2025
DOI: 10.56201/ijhpr.vol.10.no3.2025.pg75.98

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Rutin Isolate of Ocimum basilicum Attenuates Testicular Toxicity in Induced Diabetic Rats on a HighFat Diet, Histomorphological, Physiological and Biochemical Insights

Ajayi OS, Akunna GG Idoko GO, Saalu LC

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Abstract

Aims: To investigate the protective effects of rutin against Streptozotocin (STZ)-induced testicular toxicity in rats fed with a High-Fat Diet (HFD), focusing on histomorphological, physiological, and biochemical changes. Study Design: Experimental study design, using a Randomized Controlled Trial (RCT) approach with animal subjects (Wistar rats). Place and Duration of Study: Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, Benue State University Makurdi, between June and September 2024.

keywords:

Rutin, Testicular toxicity, Streptozotocin, High-fat diet, Diabetes, Spermatogenesis.

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