INTERNATIONAL JOURNAL OF HEALTH AND PHARMACEUTICAL RESEARCH (IJHPR )

E-ISSN 2545-5737
P-ISSN 2695-2165
VOL. 10 NO. 3 2025
DOI: 10.56201/ijhpr.vol.10.no3.2025.pg64.74


Presentation and Outcome of Treatment of Chronic Osteomyelitis at the Rivers State University Teaching Hospital, Port Harcourt, Nigeria

Mike Tochi Achor, Friday, Enwumelu Aaron, Tonye Adayi Obene, Rex Friday Ogoronte Alderton Ijah


Abstract


Background: The management of chronic osteomyelitis remains a challenge to the orthopaedic surgeon, often requiring multiple procedures. The aim of this study was to determine the pattern of presentation and the outcome of treatment of chronic osteomyelitis of the long bones in a teaching hospital in South-South region of Nigeria. Materials and Methods: A retrospective descriptive study was conducted among patients who had chronic osteomyelitis over a five-year period, using hospital records. The obtained data was analysed and formed into tables and figures.


keywords:

Chronic osteomyelitis, Long bones, Port harcourt, Nigeria.


References:


1. Lew DP, Waldvogel FA. Osteomyelitis. Lancet. 2004; 364:369-70.
Schmitt SK. Osteomyelitis. Infect Dis Clin North Am. 2017; 31 (2): 325-338.
Klenerman L. A history of osteomyelitis from the Journal of Bone and Joint Surgery: 1948 to
J Bone Joint Surg [Br]. 2007; 89:667-70.
Uckay I, Jungun K, Gamulin A, Wagener J. Chronic osteomyelitis. Current Infectious Disease
Reports. 2012; 14 (5): 566-75.
Cierny 3rd G, Mader JT, Pennick JJ. A clinical staging system for adult osteomyelitis. Clin
Orthop Relat Res. 2003; 414:7-24.
Legout L, Assal M, Rohner P, et al. Successful treatment of Candida parapsilosis (fluconazole-
resistant) osteomyelitis with caspofungin in a HIV patient. Scand J Infect Dis. 2006; 38:728-30
Blyth CC, Gomes L, Sorrel TC, et al. Skull –base osteomyelitis: fungal vs. bacterial infection.
Clin Microbiol Infect. 2011; 17:306-11.
Karamanis EM, Matthaiou DK, Moraitis LI, Falagas ME. Fluoroquinolones versus beta-lactam
based regimens for the treatment of osteomyelitis: a meta-analysis of randomized controlled trials.
Spine. 2008; 33:297-304.
Beals RK, Bryant RE. The treatment of chronic open osteomyelitis of the tibia in adults. Clin
Orthop Relat Res. 2005; 433:212-38.
Uckay I, Pittet D, Vaudaux P, et al. Foreign body infections due to Staphylococcus epidermidis.
Ann Med. 2009; 41:109-19.
Haider R, Der Boghosian A, Atiyeh B. Duration of post-surgical antibiotics in chronic
osteomyelitis: empiric or evidence-based? Int J Infect Dis. 2010; 14:725-8.
Lipsky BA, Berendt AR, Deery HG, et al. Diagnosis and treatment of diabetic foot infections.
Plast Reconstr Surg. 2006; 117:212-38.
Calhoun JH, Manring MM. Adult Osteomyelitis. Infect Dis Clin North Am. 2005; 19(4):765-
Benard L, Uckay I, Vuagnat A, et al. Two consecutive deep sinus cultures predict the pathogen
of osteomyelitis. Int J Infect Dis. 2009; 14: 390-3.
Mackowiak PA, Jones SR, Smith JW. Diagnostic value of sinus-tract cultures in chronic
osteomyelitis. JAMA. 1978; 239:2772-5.
McGregory JE, Pritchard DJ, Unni KK, Ilstrup D, Rowland CM. Malignant Lesions Arising
in Chronic Osteomyelitis. Clin Orthop Relat Res. 1999; (362): 181-9.
Mathews JA, Ward J, Chapman TW, Khan UM, Kelly MB. Single-stage Orthoplastic
Reconstruction of Gustilo-Anderson Grade III Open Tibial Fractures Greatly Reduces Infection
Rates. Injury. 2015; 46:2263-6.
Nwagbara IC, Opara KO. Chronic Osteomyelitis of the Long Bones. Orient Journal of
Medicine 2017; 29(3-4): 91-97.
Eyichukwu GO, Anyaehie UE. Outcome of Management of Chronic Osteomyelitis at National
Orthopaedic Hospital, Enugu. Niger J Med. 2009; 18(2): 194-198.
Alonge TO, Ogunlade SO, Omololu AB. The Belfast Technique for the Treatment of Chronic
Osteomyelitis in a Tropical Teaching Hospital. International Orthopaedics (SICOT). 2003;
27:125-128.
Onumiya JE, Onobowale BO. Outcome of Chronic Osteomyelitis in Nigeria. Journal of
Applied Basic Sciences. 2003; 1(1&2): 27-30.
Katchy NA, Agu CT, Nwankwo EO. Chronic Osteomyelitis in 110 patients. Niger Postgrad
Med J. 2000; 7(2): 49-53.
Solomon I, Warwick D, Nayagam S, editors. Apley’s Systems of Orthopaedics and Fractures,
8th ed. London: Arnold; 2001. p27-48.
Kremers HM, Nwojo ME, Ransom JE, et al. Trends in the Epidemiology of Osteomyelitis: A
population-based study, 1969- 2009. J Bone Joint Surg Am. 2015 20; 97(10): 837- 845.
Wordsworth P. Diseases of Bone and Joints: In Infections. In: Russel RCG, Williams NS,
Bulstrode CJK, editors. Bailey and Love’s Short Practice of Surgery, 24th ed. London: Arnold;
p. 479-430
26, Zhou J, Li Y, Wang QK, et al, Status of Road Safety and Injury Burden in China. J Orthop
Trauma. 2014; 28 Suppl 1: S41-S42.
Conterno LO, Turchi MD. Antibiotics for Treating Chronic Osteomyelitis in Adults. Cochrane
Database Syst Rev. 2013; 9: Cd004439.
Lazzarini L, Mader JT, Calhoun JH. Osteomyelitis in Long Bones. J Bone Joint Surg [Am].
2004; 86-A:2305-18.


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