INTERNATIONAL JOURNAL OF HEALTH AND PHARMACEUTICAL RESEARCH (IJHPR )
E-ISSN 2545-5737
P-ISSN 2695-2165
VOL. 10 NO. 2 2025
DOI: 10.56201/ijhpr.vol.10.no2.2025.pg43.65
Egoro Emmanuel Tonbra, Ilegbedion Ikhide Godwin, Amaihunwa Kingsley Chukwuka
Garri processing is a technique for converting cassava roots into garri, a granular flour with a range of textures derived from cassava tubers. This study aims to investigate the occupational effect of garri processing on some biochemical and haematological parameters among chronic processors in Amassoma, Bayelsa State, Nigeria. Ten millilitres of blood samples were obtained via venipuncture technique from eighty garri processors, who were categorised into experimental group one, comprising forty processors with < 10 years processing experience and experimental group two, consisting of forty processors with 10-15 years processing experience. The control group consisted of fifteen non-garri processors. Five millilitres of the blood samples were dispensed into lithium heparin anti-coagulated bottle for the measurement of the following biochemical parameters: alanine aminotransferase, aspartate aminotransferase, creatinine, urea, C-reactive protein, interleukin-6, malondialdehyde and glutathione peroxidase while the remaining five millilitres were dispensed into ethylene diamine tetraacetic acid anti-coagulated bottles for the measurement of the following haematological parameters: packed cell volume, haemoglobin, total white blood cell count, neutrophil count, lymphocyte count, eosinophil count, monocyte count and basophil count employing SPSS version 23.0 for statistical analysis. In experimental group one, the findings indicated increases in the mean values of the following biochemical parameters: C-reactive protein (p=0.03), interleukin-6 (p = 0.03), malondialdehyde (p = 0.03) and glutathione peroxidase (p = 0.03) while the other parameters were not significantly altered (p > 0.05) as compared to the control group. In experimental group two, alanine aminotransferase (p = 0.04), aspartate aminotransferase (p = 0.04), C-reactive protein (p = 0.01), interleukin-6 (p = 0.01), malondialdehyde (p = 0.02) and glutathione peroxidase
Occupational effect, garri processing, biochemical parameters, haematological
Abass, B.A., Dziedzoave, T. N., Alenkhe, E. B. and James, B. D. (2013). Quality management
manual for the production of garir. International Institute of Tropical Agriculture.
Adebayo, A.A. et al. (2024). Haematological changes in garri processors in Osogbo, Osun State,
Nigeria. Journal of Environmental and Occupational Science. 6 (2):1-6
Akinwum,i O.O. et al. (2017). Neutrophils and lymphocyte counts in garri processors in Ibadan,
Oyo State, Nigeria. Journal of Environmental and Occupational Science. 6 (1):1-6
Akinwumi, S.A. et al. (2017). Haematological effects of garri processing on female processors jn
Ghana, Journal of Applied Haematology. 8 (2):1-6
Alimi, A.K. and Animashaun, A. W. (2024). Health related problems associated with women garri
producers in agricultural zone. Association of Southeast Asian Nations (ASEAN) Journal of
Agriculture and Food Engineering, 3 (1): 23 -30.
Amadi, C.N. et al. (2020). Evaluation of oxidative stress and inflammatory markers in garri
processors in Nigeria. Journal of Environmental and Occupational Science. 9 (1):1-7
Automated Haematology Analyser. Clinical and Laboratory Standards Institute (2019).
Haematology and Coagulation Devies. Approved Standard. CLS Document H59-A
Baker, J.F., Silver, E.R. and Kilshaw, D. (1998). Full blood count. In Introduction to Medical
Laboratory Technology. 7th Edtion, London Edward Arnold
Clinical and Laboratory Standards Institute (2019). Haematology and coagulation devices
approved standard. CLS document H59-A
Cock, H. J. and Connor, J. D. (2021) Cassava. Crop physiology case histories for major crops,
588-633.
Dapamowei, H.A. (2018). A historical evolution and development of Amassoma Seigbein fishing
festival in central Niger Delta region of Nigeria. Abraka Humanities Reviews 8 (1): 137-158
Egoro, E.T., Ilegbedion, I.G. and Hope, C (2023). Status of some biochemical markers among
nasal tobacco snuffing addicts in Yenagoa, Bayelsa State, Nigeria. International Journal of
Medical Evaluation and Physical Report. 7 (4): 135-144
Egoro, E.T.., Musa, A.S. and Ilegbedion, I.G. (2024). Status of some toxic heavy metals, oxidative
stress and inflammatory biomarkers among petty traders in Swali market, Yenagoa, Bayelsa
State, Nigeria. IOASD Journal of Medical and Pharmaceutical Sciences. 1 (1):28-33
Egoro, E.T.., Oni, E.S. and Ifenkwe, J.C. (2024). Effect of chronic exposure to petroleum products
on some hepato-renal, toxico-inflammatory and cardiac biomarkers among auto-mechanics in
mechanic village, Yenagoa, Bayelsa State, Nigeria. International Journal of Chemistry and
Chemical Processes. 10 (4): 32-46
Egoro, E.T.., Oni, E.S. and Ilegbedion, I.G. (2024). Evaluation of some cardio-inflammatory,
hepato-renal, reproductive hormones and oxidative stress biomarkers among post-menopause
women in Amassoma, Bayelsa State, Nigeria. International Journal of Medical Evaluation and
Physical Report. 8 (6): 20-35
Emmanuel, T.E., Ikhide, G.I. and Sonia, O.A. (2020). Biochemical and histomorphological
changes in liver and kidney of Rattus norvegicus domestica rats following tetracycline
administration. GSC Biological and Pharmaceutical Sciences. 12 (02): 238-245
Ezeh, C.C. et al. (2018). Lymphocyte and neutrophil counts in garri processors in Port-Harcourt,
Rivers State, Nigeria. Journal of Medical and Biomedical Sciences. 7 (1):1-6
Ezeijofor, A.N. et al. (2019). Erythrocytes sedimentation rate and haemoglobin levels in garri
processors in Enugu, Enugu State, Nigeria. Journal of Medical and Biochemical Sciences. 8
(1):1-6
Food and Agriculture Organization of the United Nations (2013). FAO statistical year book 2013:
World food and agriculture. Food and Agriculture Organization
Fosu-Mensah, B. Y., Adabie, F. D., Paa-Nii, J.T. and Mensah, M. (2021). Occupational and
environmental health hazards associated with food processing and the use of personal
protective equipment: A case study of gari processing in Southern Ghana. Journal of Applied
and Natural Science, 13 (1): 230 -237.
Igwe, R.O. et al. (2020). Haematological and biochemical changes in garri processors in Enugu,
Nigeria. Journal of Medical and Biomedical Sciences. 9 (1):1-9
International Council for Standardization in Haematology (1980). Packed cell volume
measurement by microhaematocrit method. Journal of Clinical Pathology. 33 (9):865-866
Iyanda, A.A. et al. (2017). Haematological and biochemical changes in garri processors in Lagos,
Nigeria. Journal of Environmental and Occupational Science 6 (2):1-6
Kampen, E.J. and Zijistra W.G. (1961). Standardization of haemoglobincyanide method. Clinica
Chimica Acta 6 (5): 538-544
Makanjuola, M. O., Ogunmodede, A. S., Makanjuola, J. O. and Awonorin, S. O. (2012).
Comparative study of quality attributes of gari obtained from some processing centres in South
West, Nigeria. Advance Journal of Food Science and Technology. 4 (3): 135-140.
Munyao, M. C., Kiptoo, K.G.K. and Simiyu, M. G. (2022). Assessment of health risks associated
with particulate matter and carbon monoxide emissions from biomass fuel utilization in
Western Kenya. European Journal of Health Sciences. 7 (5): 39 -57.
Nwankwo, et al. (2020). Haematological changes in garri processors in Onitsha, Anambra State,
Nigeria. International Journal of Medicine and Biomedical Research. 9 (1):1-8
Nwosu, D.C. et al. (2019). Haematological changes in garri processors in Cameroon Journal of
Medical and Biomedical Sciences 8 (1):1-6
Ogbodo, R.N. et al. (2021). Haematological effects of garri processing on processors in Nigeria.
Journal of Environmental and Occupational Health. 10 (1):1-6
Ogbonna, C.E. et al. (2018). Assessment of haematological and biochemical parameters in garri
processors in Ghana. Journal of Medical and Biomedical Sciences. 7 (1):1-8
Ogbonna, C.E. et al. (2018). Haematological alterations in garri processors in Aba, Abia State,
Nigeria. International Journal of Haematology and Blood Disorders. 3 (1):1-8
Okogbenin, E., Fregene, M., Ceballos, H., Egesi, C., Fulton, T. and Alves, A. (2012). Cassava
research in Nigeria. Umudike, Nigeria: National Root Crops Research Centre.
Okwor, J. T., Ozoh, B. O., Okonkwo, I. J. and Osibogun, A. (2017). Occupational exposure to
particulate matter from biomass smoke and its relationship to respiratory symptoms and
pulmonary function among rural women involved in cassava processing in Nigeria. Open
Journal of Preventive Medicine. 7 (3): 41 -54.
Omolola, O.A., Kwaku, P.A., Kenneth, A.A. Ellen, A.B., Oscar, A. and Reggie, Q. (2020).
Exposure to carbon monoxide and particulate matter among cassava grit processors in the
middle belt of Ghana: a cross-sectional study. Pan African Medical Journal. 37 (181): 1-10.
Sherifat, T. A and Wunmi, A.A. (2018). Microbial evaluation of garri sold in Ijebu community.
IOSR Journal of Environmental Science, Toxicology and Food Technology. 12 (7): 35 -38.
Westergren, A. (1921). The techniques of red cell sedimentation reaction. American Journal of
Clinical Pathology. 1(2): 137-145
World Medical Association Declaration of Helsinki-Rthical Principles for Medical Research
Involving Human Subjects Adpoted by the 59th World Medical Association General Assembly,
Seoul Republic of Korea, October, 2008