IIARD International Institute of Academic Research and Development

JOURNAL OF BIOLOGY AND GENETIC RESEARCH (JBGR )

E-ISSN 2545-5710
P-ISSN 2695-222X
VOL. 10 NO. 2 2024
DOI: 10.56201/jbgr.v10.no2.2024.pg127.132

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The Roles Suppressor of Cytokine Signaling 7 SOCS7) Gene in Bombyx mori (Silkworm) against Bombyx mori Nucleopolyhedrosis Virus (BmNPV) infection: A Review

Idris I, Abba D, Abba M, Ibrahim ZY, Umar AN, Buhari A, Sani A, Adam SS and Ali M

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Abstract

Bombyx mori silkworm belongs to the family of Bombycidae and the order Lepidoptera which are known to have originated and domesticated in China about 5,000 years ago. Silkworm is also a good model organism for production of recombinant proteins and the study of insect immunology. However, its populations are severely threatened by BmNPV, a virus that causes high mortality rates and reduced silk yield. B. mori nucleopolyhedrovirus (BmNPV) is a primary silkworm pathogen, and always causes serious economic losses. The paper review, the current understanding of silkworm suppressor of cytokine signal 7 (SOCS7) and its role in antiviral immunity against BmNPV infection, highlighting the insights gained from the silkworm infection model and functional analysis of SOCS7.

keywords:

Bombyx mori, B. mori nucleopolyhedrovirus (BmNPV), silkworm, SOCS7

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