IIARD International Institute of Academic Research and Development

JOURNAL OF BIOLOGY AND GENETIC RESEARCH (JBGR )

E-ISSN 2545-5710
P-ISSN 2695-222X
VOL. 10 NO. 2 2024
DOI: 10.56201/jbgr.v10.no2.2024.pg98.105

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Effect of Kefir on Glucose Concentration and Blood Biochemical Parameters in Alloxan??nduced Diabetes Mellitus Rabbits

Ahmed Adnan Abbas Skrane

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Abstract

Kefir, a traditionally fermented beverage derived from milk, harbors a diverse microbial community that imparts a wide range of health benefits, including potential anti-diabetic properties. In this study, we investigated the potential positive effects of kefir consumption on blood parameters and blood glucose levels in diabetic rabbits. A total of 48 rabbits with an initial weight of 250 grams were divided into four research treatments (Control, DM+kefir: diabetic rabitts + 3.6 ml kefir/ 200 g rabitts, DM+Gliben: diabetic rabitts + 600 ?g Glibenclamide /kg rabitts) and kept under standard conditions for 40 days. Blood parameter measurements were conducted on the 20th and 40th days of the experiment. The results revealed consistent findings for the evaluated indicators across both time points. Significant differences (P<0.05) were observed in the levels of cholesterol, triglycerides, glucose, and LDL between the treated diabetic rabbits and the control group. Furthermore, the diabetic rabbits exhibited significantly lower levels of HDL compared to the control group (P<0.05). Notably, the use of kefir as a treatment led to a significant reduction in these indicators, which were significantly different from the diabetic treatment group (P<0.05). Interestingly, no significant difference was observed between the kefir treatment and the Glibon drug, as indicated by several indicators (P>0.05). These findings highlight the potential beneficial effects of kefir on blood parameters in diabetic rabbits.

keywords:

Kefir, rabitts, diabetics, Glibenclamide, glucose, lipid

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