IIARD International Institute of Academic Research and Development

INTERNATIONAL JOURNAL OF MEDICAL EVALUATION AND PHYSICAL REPORT (IJMEPR )

E-ISSN 2579-0498
P-ISSN 2695-2181
VOL. 8 NO. 3 2024
DOI: https://doi.org/10.56201/ijmepr.v8.no3.2024.pg1.8

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Phytoconstitution and Antioxidant Evaluation of the Ethanolic Leaf and Stem Bark Extracts of Soursop (Annona muricata)

Edet O. Odokwo and Ngozi M. Uzoekwe

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Abstract

The qualitative and quantitative phytoconstitution and the quantitative antioxidant activity evaluation of the leaves and stem of soursop (Annona muricata) have been carried out. The plant parts were collected from Otuoke community, Ogbia Local Government Area of Bayelsa state, Nigeria. The parts were chopped separately, dried, extracted with absolute ethanol and then concentrated under vacuum. The leaf extract (IDL) and stem extract (IDS) were evaluated for their phytoconstitution using standard procedures and the in vitro antioxidant activity using 1,1- diphenyl picrylhydrazine (DPPH) technique. Phytochemicals such as alkaloids, phenols, flavonoids, glycosides, tannins, saponins and terpenoids were detected and quantified in comparative levels in mg as: (alkaloids, 13.0), (phenols, 0.440), (flavonoids, 8.3 ×10 -5 ), (cardiac glycosides, 486.0), (tannins, 10.6) and (terpenoids, 322.0) in the leaves and (alkaloids, 20), (phenols, 0.70), (flavonoids, 8.2 ×10 -5 ), (cynogenic glycosides, 300.0), (tannins, 6.20) and (terpenoids, 215.0) in the stem with no significant different at p < 0.05 using t-test statistical analysis. The DPPH assay revealed that both IDL and IDS exhibited antioxidant activity in a dose gradient concentration of 1.0 mg/ml to 0.625 mg/ml. the present study has established that both the leaves and stem bark of soursop have phytochemicals and do exhibit antioxidant activity.

keywords:

Soursop, phytochemicals, antioxidant

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References:

Agu, K.C. and Okolie, P.N. (2017). Proximate composition, phytochemical analysis, and in vitro
antioxidant potentials of extracts Annona muricata (soursop). Food Sci Nutr., 5(5), 1029-
1036.

Agu, K.C., Okolie, N.P., Eze, G.I., Anionye, J.C. and Falodun, A. (2017). Phytochemical analysis,
toxicity profile and hemo-modulatory properties of Annoma muricata (soursop). Egyptian
Journal of Haematology, 42, 36-44.

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