IIARD International Institute of Academic Research and Development

INTERNATIONAL JOURNAL OF CHEMISTRY AND CHEMICAL PROCESSES (IJCCP )

E-I SSN 2545-5265
P- ISSN 2695-1916
VOL. 9 NO. 3 2023
DOI: https://doi.org/10.56201/ijccp.v9.no3.2023.pg1.9

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Comparative Analysis of The Essential Chemical Components in Two Commercial Antibiotics

A.U.G.Okeke , F.C. Ikechukwu , Ezetoha, N.O. and Orakwe, F.C

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Abstract

The experiment was carried out to comparatively analyze the active ingredients present in Ampiclox and Amoxicillin. The experiment was successfully carried out using standard analytical methods. The result obtained showed no significance difference in the absorbance of the samples tested. The experiment shows that the quantities of the samples for Ampiclox are 682mg for Beecham, 690mg for Reichlox and 740mg for vadisclox while for Amoxicillin are 461mg for Vamoxil, 463mg for Noxil and 463mg for GSK. The result obtained shows that the quantity obtained for the Ampiclox samples were higher than the label quantity of 500mg while the quantity obtained for the Amoxicillin samples were lower than the label quantity of 500mg. It was however suggested that more studies should be carried out on this topic and also the purity of active ingredients imported from abroad should always be investigated and determined properly as it affects the quality of drugs produced with them.

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References:

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Batchelor, F.R., Doyle, F.P; Naylor, J.H.C; Rolinson, G.N. (1959). “Synthesis of Penicillin: 6-
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Burley, J.C.; Van de Streek, J., Stephens P.W. (2006). “Ampicillin trihydrate from synchrotron
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