IIARD International Institute of Academic Research and Development

INTERNATIONAL JOURNAL OF MEDICAL EVALUATION AND PHYSICAL REPORT (IJMEPR )

E-ISSN 2579-0498
P-ISSN 2695-2181
VOL. 5 NO. 1 2021

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Immunohaematological Reference Values of Apparently Healthy Adult Nigerians in Benin City, Edo State.

Nweke, J.N. and Jeremiah Z.A.

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Abstract

Background: Full blood analysis is the most frequently ordered blood investigation panel by medical practitioners. Aim: This study was set out to determine a locally based immunohaematological reference values for apparently healthy adult Nigerians in Benin City, Edo state. Methods: The research was carried out in Benin City within the three local government areas which comprise Oredo, Ego and Ikpoba-Okha local council areas of the state, with a total of three hundred (300) subjects aged between 20 to 50 years comprising 150 males and 150 females who were randomly enrolled. Reference ranges were calculated using nonparametric methods. Result: The immunohaemmatological reference values of this study presents as follows: The total white blood cell count show a reference range of 4.3 – 10.0 (109/l); lymphocytes 22.1 - 42.0 (%); neutrophils 50.1 - 73.0 (%); red blood cells 3.8 - 5.4 (1012/l); haemoglobin 11.0 - 16.0 (g/dl); haematocrit 33.9 - 49.8 (%); mean corpuscular volume 73.0 - 94.0 (%); mean corpuscular haemoglobin 4.0 – 36.0 (%); mean corpuscular haemoglobin concentration 24.0 - 38.6 (%); platelets 150 – 305 (109/l); and cluster of differentiation (CD4+) cell count of 419 – 1807 cells/ul. Discussion: The result obtained showed a slight significant differences with a higher mean red blood cells, haemoglobin, haematocrit, mean cell volume, and mean corpuscular haemoglobin values in the males than the females (p < 0.05). There is however, no significant difference in the CD4+ values (p > 0.05).The study also shows a distribution of immunohaematological indices along age boundaries as there are slight significant differences in red blood cell, white blood cell, and platelet distribution between the age groups, with the highest mean value in age group 40 to 49, and lowest mean value in age group 20 to 29 (p < 0.05). Conclusion: It is expedient to provide region-specific reference values which could be used to guide patient management plans, in

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